Fine lines and wrinkles are a natural part of aging, but modern neuromodulators offer fast and effective ways to smooth them. Jeuveau, Botox, and Dysport are all forms of botulinum toxin type A (BoNT-A) that relax targeted facial muscles and soften wrinkles. Yet there are subtle differences in how each works, how quickly they kick in, and how long results last.

This guide breaks down each treatment, compares them side by side, and walks through what to expect before and after your appointment.

Meet the Wrinkle Relaxers

Botox (OnabotulinumtoxinA)

  • Overview: 
    • Botox is the most widely known neuromodulator and has been FDA-approved for both cosmetic and medical use for decades.
    • Cosmetically, it treats forehead lines, crow’s feet, and glabellar frown lines.
    • Medically, it is also used for chronic migraines, excessive sweating, overactive bladder, and certain muscle disorders.
  • Onset & Longevity: 
    • Botox typically begins working within 3–5 days, with full results noticeable at around two weeks.
    • Results last about 3–4 months on average, although some patients may experience longer-lasting effects depending on their metabolism, muscle strength, and treatment area.
  • Pros: 
    • Extensive safety record: Over 20 years of use worldwide with FDA approval across multiple conditions.
    • Consistent results: Reliable for smoothing moderate to severe facial lines in multiple areas.
    • Versatility: Approved for both cosmetic and medical applications.
    • Strong brand recognition: Patients often feel confident choosing Botox due to its trusted reputation.
  • Cons:
    • Slightly slower onset than Dysport, which may kick in faster.
    • Cost considerations: Per-unit pricing can be higher than alternatives such as Jeuveau, although fewer units may sometimes be required.
    • Temporary results: Requires repeat treatments every few months to maintain benefits.

What to Expect: Procedure & Recovery

A Botox session lasts about 10–20 minutes. Your provider will use a fine needle to inject precise amounts into targeted muscles. You can resume normal activities right away, but it’s best to avoid strenuous exercise for 24 hours. Results generally last 3–4 months.

Dysport (AbobotulinumtoxinA)

  • Overview: 
    • Dysport is another FDA-approved neuromodulator with a smaller molecular size, Dysport spreads more easily once injected.
    • Effective for treating larger areas such as the forehead.
    • Dysport relaxes targeted muscles to smooth moderate to severe wrinkles and prevent deepening of facial lines.
  • Onset & Longevity: 
    • Dysport’s biggest advantage is its quick onset.
    • Results often begin to appear within 2–3 days.
    • Full results are usually visible in about a week and effects last approximately 3–4 months.
    • Some patients report that Dysport may last slightly longer in certain areas.
  • Pros: 
    • Fast-acting: Noticeable improvements in as little as 2–3 days.
    • Natural appearance: Provides smooth, subtle results without a “frozen” look.
    • Ideal for large areas: Greater spread makes it well-suited for broad treatment zones like the forehead.
    • Additional benefit: Some studies suggest Dysport may help reduce oil production, potentially improving skin texture.
  • Cons: 
    • Diffusion factor: While spread is beneficial for larger areas, it can be risky near delicate or small muscles where precision is crucial.
    • Dosing differences: Requires different unit measurements than Botox, so patients may need more units, which can affect cost comparisons.
    • Temporary results: Just like other neuromodulators, results are not permanent and require repeat treatments.

What to Expect: Procedure & Recovery

Treatment takes 10–15 minutes, with injections placed into the target muscles. Many patients see improvement in 2–3 days. Mild swelling or tenderness may occur, but downtime is minimal. Results typically last 3–4 months.

Jeuveau (PrabotulinumtoxinA)

  • Overview:
    • Jeuveau is the newest FDA-approved neuromodulator on the market.
    • It is structurally very similar to Botox, sharing the same core mechanism of action by temporarily relaxing facial muscles to smooth dynamic wrinkles.
    • Jeuveau is approved exclusively for cosmetic use and is not indicated for medical conditions.
  • Efficacy & Safety: 
    • Clinical studies have shown Jeuveau to be non-inferior to Botox in treating frown lines, meaning it works just as effectively in head-to-head comparisons.
    • Many patients experience smoother, more youthful-looking skin with a high level of satisfaction.
  • Onset & Longevity: 
    • Noticeable improvements within 3–5 days. 
    • However, the average duration is around 3–4 months.
  • Pros: 
    • Affordable option: Often priced more competitively than Botox.
    • Effective results: Proven efficacy for smoothing frown lines with natural-looking outcomes.
    • Cosmetic focus: Specifically designed and marketed for aesthetic treatments.
    • Strong safety record: Favorable clinical trial results and FDA approval for cosmetic use.
  • Cons: 
    • Fewer approved areas: Currently limited to treating glabellar lines.
    • Less history of use: Since it is newer to the market, it lacks the decades-long track record of Botox.
    • No medical uses: Unlike Botox, it is not approved for therapeutic applications such as migraines or muscle disorders.

What to Expect: Procedure & Recovery

Treatment typically takes 10–20 minutes. Small injections are placed directly into targeted muscles. Most patients can return to daily activities immediately, though minor redness or swelling at injection sites is common for a few hours. Results usually last 3–4 months.

Potential Side Effects

While generally safe when performed by an experienced provider, possible side effects include:

  • Temporary redness or swelling at the injection site
  • Bruising
  • Headache
  • Eyelid or brow drooping (rare and temporary)

Which Option Is Right for You?

Choosing between Jeuveau, Botox, and Dysport depends on factors like your budget, how quickly you want to see results, the size of the treatment area, and your personal preferences. During your consultation, Dr. Rochlin will evaluate your goals, facial anatomy, and prior injectable history to recommend the most effective option.

Side-by-side comparisons

Feature Botox Dysport Jeuveau
Onset Results 3-5 days 2-3 days 3-5 days
Duration 3-4 months 3-4 months 3-4 months
Best For Multiple areas Large treatment area Forehead/frown lines
Cost Higher per unit Moderate Lower per session
Diffusion/Spread Moderate Higher Moderate
FDA Approval Area Multiple cosmetic and medical uses Cosmetic/docs for wrinkles Cosmetic use only for glabellar lines

Patient Testimonials:

“Have been to this practice several times for fillers and peels. The results have always been amazing and the staff extremely friendly I recommend using this practice”-K.R

“I’ve been seeing Dr. Rochlin for the last four years and wouldn’t trust anyone else for Botox and fillers!”-M.C

Ready to refresh your look?

You’ve taken the first step by understanding your options, but the most important step is a personalized consultation. While this guide provides an overview, the right treatment for you depends on your unique facial anatomy, specific concerns, and desired outcomes.

Don’t just choose a treatment; choose an expert who will guide you to the perfect solution. Schedule your consultation with Dr. Rochlin today and take the first step toward a more confident you.